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What is the confirmatory test for a typhoid fever?

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Laboratory Studies. The diagnosis of typhoid fever (enteric fever) is primarily clinical. Importantly, the reported sensitivities of tests for S typhi vary greatly in the literature, even among the most recent articles and respected journals. read more

A positive blood culture is the only confirmatory test for diagnosis of typhoid fever and other laboratory tests are not diagnostic. There may be non specific laboratory changes like leukopenia and neutropenia in 15% to 25% of the cases of typhoid fever and also moderately elevated liver function tests and muscle enzyme levels. read more

New commercially available typhoid rapid antibody tests have been evaluated in Asia, where typhoid fever is known to be highly endemic. 1, 5 In Asian studies the tests have shown variable performance. read more

The Widal test (Widal’s agglutination reaction) is routinelypractised for the serodiagnosis of typhoid fever by most ofthe laboratories. Several workers have expressed doubtregarding the reliability of the test. read more

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