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What is the difference between despair and sadness?

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When your dad dies, you feel sad, genuinely sad; and that's okay. It's normal, good, survivable. When your dad dies, your kids leave you, you lose your job, your wife divorces you, you lose your house... read more

As nouns the difference between despair and depression is that despair is loss of hope; utter hopelessness; complete despondency while depression is (lb) an area that is lower in topography than its surroundings. As a verb despair is (obsolete) to give up as beyond hope or expectation; to despair of. read more

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Further Research

Despair vs Depression
wikidiff.com

Despair vs Sadness
wikidiff.com

Removing Despair from Depression
www.psychologytoday.com

Sadness, Depression and Despair
www.allianceofhope.org