What is the effect of excess phospholipids in CSF?

Additionally, investigation has extended changes in the CSF to lipids and nucleic acids. ... Tourtellotte and colleagues established a formula for the determination of intrathecal IgG synthesis for a 24 hour period and values in excess of 4 mg per 24 h period (or values established by the laboratory) were considered abnormal. read more

Interesting question. I wonder if it is really a question of phospholipid quantities in CSF as an indication of brain trauma or neurological disease, rather than phospholipids per set as causative of neurological problems. read more

Excessive production of fluid or obstruction to the circulation of the fluid due to closure of drainage channels can result in excessive quantity of fluid within the brain ventricles (spaces in the brain) and spinal cord, resulting in increased pressure of the fluid. read more

When hydrocephalus occurs in adults, CSF levels rise but the amount of pressure is usually normal. It still causes the brain to swell and can lead to impaired functioning. In adults, this condition usually results from conditions that prevent CSF from flowing. read more