What is the interaction between levothyroxine and grapefruit?

Conclusions. Grapefruit juice may slightly delay the absorption of levothyroxine, but it seems to have only a minor effect on its bioavailability. Accordingly, the clinical relevance of the grapefruit juice-levothyroxine interaction is likely to be small. Keywords: food-drug interaction, grapefruit juice, levothyroxine. read more

Applies to: Synthroid (levothyroxine) The timing of meals relative to your levothyroxine dose can affect absorption of the medication. Therefore, levothyroxine should be taken on a consistent schedule with regard to time of day and relation to meals to avoid large fluctuations in blood levels, which may alter its effects. read more

So the plan is this: Levothyroxine (probably) 150mcg Femara 10mg CD3-7 Grapefruit Juice at least 1 glass per day CD 8 til O OPKs will start at the end of Femara since I got my positive last cycle on CD10. read more