What is the most complex manufacturing process?

Bombers since at least the 1930's and beyond the capabilities of most countries, let alone manufacturers within them. Hundreds of thousands of pieces, all of them very short production runs if not customized and constantly changing (upgrades, repl... read more

d) The change relates to all other pharmaceutical forms manufactured by complex manufacturing processes . The EMA now clarified this term as follows: Guideline Change Code B.II.b.1: Complex manufacturing processes are given when the understanding of the relation between quality characteristics of the product and its in vivo efficacy is lacking. read more

In addition, the process often operates through heuristics due to incomplete understanding of all process parameters and variability in environmental operating conditions. Also, the process is not complete until all or most stages are complete; disruptions in the process often result in rejection of the batch. read more