What is the strongest pain killer known to man?

It's not surprising, then, that pain medications, also known as analgesics, are among the most commonly used drugs in the U.S. Different medications are used depending on the type of pain. ... But the strongest opioid in community use is fentanyl which, in its intravenous form, is 70 to 100 times more potent than morphine. read more

CII's tend to be the stronger ones, like Morphine, oxycontin/oxycodone, oxymorphone, hydromorphone methadone and fentanyl. CII's have the highest abuse potential, CIII's are next strongest. This includes drugs like Tylenol with codeine, hydrocodone, propoxyphene (which is no longer on the US market). read more

All narcotic agents have a dissociative effect that helps patients manage pain. It does not actually deaden the pain, but works to dissociate patients from the pain. Commonly used narcotics, listed in ascending order of potency (strength) include: codeine; propoxyphene (e.g. Darvocet); hydrocodone (e.g. Vicodin); oxycodone (e.g. Percocet, Oxycontin). read more