What is the wobble effect of tRNA?

The wobble effect is an effect caused by the redundancy found in the genetic code. Each amino acid is coded for by a 3 nucleotide sequence on the mRNA. The triplets are referred to as codons. read more

Wobble base pairing enables the decoding of two or more codons by the same tRNA. Certain modified bases, for example inosine (I) can extend or restrict the degree of flexibility in the range of mRNA: tRNA interactions. Codons that are decoded by wobble base interactions are processed at a slower rate in the ribosome. read more

I would guess that there are similiar hydrogen bonds being formed when this wobble effect occurs and can maybe take a different amino acid, with a different sequence. Another idea is that the tRNA is easier to recycle (i.e. tRNA's with similiar anticodon sequences) and can change the bases easily. read more