Leptin decreases hunger. Ghrelin is secreted primarily in the lining of the stomach. Ghrelin increases hunger. Both hormones respond to how well-fed you are; leptin usually also correlates to fat mass — the more fat you have, the more leptin you produce. read more
Leptin is a hormone, made by fat cells, that decreases your appetite. Ghrelin is a hormone that increases appetite, and also plays a role in body weight. Levels of leptin -- the appetite suppressor -- are lower when you're thin and higher when you're fat. read more
It is your body's natural weight control mechanism. And the great thing about leptin is that it is produced naturally in the body. Leptin regulates metabolism and appetite: It lets your brain know how much fat is in your body. As leptin levels rise, your appetite diminishes. As leptin levels fall, your appetite increases. read more