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When are genetic mutations most likely to occur?

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Mutations are most frequent when an individual is repeatedly exposed to extremely carcinogenic compounds, such as Benzo(a)pyrene and the like. read more

Mutations are most frequent when an individual is repeatedly exposed to extremely carcinogenic compounds, such as Benzo(a)pyrene and the like. Such exposure to compounds such as benzo(a)pyrene (a product of inefficient combustion reactions) often alters the chemical structure of DNA, resulting in transcription errors at a much higher frequency than normally observed. read more

Most disease-causing gene mutations are uncommon in the general population. However, other genetic changes occur more frequently. Genetic alterations that occur in more than 1 percent of the population are called polymorphisms. They are common enough to be considered a normal variation in the DNA. read more

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The causes of mutations
evolution.berkeley.edu