Since its introduction in 1948, has proven to be remarkably effective for enteric fever worldwide. For sensitive strains, still most widely used antibiotic to treat typhoid fever. read more
Typhoid fever is caused by Salmonella typhi (more accurately, Salmonella enterica serovar Typhi). This organism used to be susceptible to plain old ampicillin in the 1960s, but later became resistant. read more
For sensitive strains, still most widely used antibiotic to treat typhoid fever. In the 1960s, S typh i strains with plasmid-mediated resistance to chloramphenicol began to appear and later became widespread in many endemic countries of the Americas and Southeast Asia, highlighting need for alternative agents. read more