Obviously, the Nook connects to the Barnes & Noble ebook store, while the Kindle connects to the Amazon Kindle store. Both stores offer all of the big-name books from popular authors, as well as a stunning selection of back-catalog items. read more
However, if you are looking for something that you can read both Amazon Kindle and Nook books as well as use it as an Android tablet to run apps go with a Nook, root it w/Cyanogen and you will have a very awesome tablet for $250 (or less with the Nook. read more
Barnes & Noble seems to have a broader selection of periodicals than Amazon does. Also, the Nook's scrubbing bar for moving forward and back in the magazine is better constructed than the one on the Kindle Fire. read more
Most e-readers have phenomenal battery life, and the Nook and Kindle are no exception. The Nook advertises six weeks of battery life, assuming 30 minutes of reading per-day, one page refresh per minute, the GlowLight at 30 percent brightness, and wireless off. read more