Nicotine was isolated from tobacco leaves (Nicotiana tabacum) in 1828, but the powerful effects of nicotine were already well recognized. The tobacco plant is native to the Americas and its use as a medicine and stimulant goes back at least 2000 years and most likely many millennia before that. read more
Nicotine was discovered by German chemists back in"1828 by physician Wilhelm Heinrich Posselt and chemist Karl Ludwig Reimann of Germany, who considered it a poison. read more
Nicotine is found in the leaves of Nicotiana rustica, in concentrations of 2–14%; in the tobacco plant, Nicotiana tabacum; in Duboisia hopwoodii; and in Asclepias syriaca. Nicotine constitutes approximately 0.6–3.0% of the dry weight of tobacco. read more