Groot hands down under virtually any circumstance unless the battle takes place in a place where Groot has no access to any soil or fertilizer. And Deadpool would still need a HUGE weapon. read more
Groot would win because he would first impale deadpool in the chest. Next he would rip his arms of. After that he probably be totally disabled for a while, so groot world probably smash his skull into a wall causing severe brain damage causing memory loss when he regenerates. As a result, Groot wins. read more