Depends on why they are fighting and what the story is leading to. For instance, I could see Patrick starting a fight over something dumb or maybe they are doing a mock wretling match but Patrick ends up being way too violent and physical, Spongeb... read more
That being said, Spongebob is the only one of the two who even practices a martial art. My take is that in a feat of shear strength Patrick would win, but I can't see Patrick successfully defeating Spongebob in a full-fledged one-on-one battle. read more