So you're basically asking why the genetic material is in the nucleus? If that's what you ask, then I think my answer might make some sense to you. * The nucleus acts like a protective barrier for the genetic material. read more
In the nucleus of each cell, the DNA molecule is packaged into thread-like structures called chromosomes. Each chromosome is made up of DNA tightly coiled many times around proteins called histones that support its structure. Chromosomes are not visible in the cell’s nucleus—not even under a microscope—when the cell is not dividing. read more
In a normal cell Nuclei, One chromosome is equivalent to 1 molecule of DNA though chromosome also associates with Histone and Non-Histone proteins where as pure DNA is a Biomolecule. And hence in a Human cell Nucleus (with no chromosomal breakages or Denaturated DNA) 46 molecules of DNA/Chromosomes are present. read more