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Why does the blood group O not have any antigen?

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“O” blood group doesn't any antigen that decides it's blood group. Antigen is a protein that situated on RBCs membrane. Antigen “A” is present on blood group “A” RBC. Antigen “B” is present on blood group “B” RBC. Antigen “A” and “B” both present on blood group “AB” RBC membrane. read more

Hence people of blood group O, lacking blood-group antigens A and B, will not have become tolerant to them, and will have antibody-producing cells capable of producing antibodies against them, should they encounter them in an incorrect blood transfusion. read more

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