Why does Vicodin cause heartburn and pain?

Vicodin (hydrocodone) is an opioid medication that has many potential side affects, mostly centrally acting in the brain and spinal cord. It also contains acetaminophen (Tylenol). Neither med is associated with causing increased gastric acid production or relaxation of the lower esophageal sphincter, which typically causes heartburn. read more

Re: Hydrocodone and GERD Prescription 'narcotic' painkillers are a HUGE culprit of causing heartburn and acid reflux - repeated use can cause severe damage to the lining of your stomach and esophogus. read more

Find information about common, infrequent and rare side effects of Vicodin Oral. read more