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Why is ethanol an antidote for methanol poisoning?

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Antidote therapy, often using ethanol or fomepizole, is directed towards delaying methanol metabolism until the methanol is eliminated from the patient's system either naturally or via dialysis. read more

The toxicity of methanol is in the by products that the body makes, when it tries to metabolize the methanol. The alcohol metabolism happens primarily in the liver. Other than the liver, it is also excreted by the lungs and kidneys. Unlike liver these organs remove the alcohol as it is. This is the reason why breathalyser works. read more

Antidote therapy, often using ethanol or fomepizole, is directed towards delaying methanol metabolism until the methanol is eliminated from the patient’s system either naturally or via dialysis. Like methanol, ethanol is metabolized by ADH, but the enzyme’s affinity for ethanol is 10-20 times higher than it is for methanol. read more

Ethanol as an antidote by Mike Cadogan, Last updated November 26, 2015 Competitively blocks the formation of toxic metabolites in toxic alcohol ingestions by having a higher affinity for the enzyme Alcohol Dehydrogenase (ADH). read more

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