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Why is Klinefelter not discoverable by 23andMe?

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This is an educated guess: My initial reaction was that it was for quality control, but having thought about it, I think it's primarily for legal reasons. read more

Source: quora.com
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Not only would this approach only detect SOME of the paternal nondisjunction events, the approach would NOT detect Klinefelter syndrome due to MATERNAL nondisjunction, since the mother’s two X chromosomes would be identical, and indistinguishable by 23andMe. read more

Source: quora.com
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