Why is LDL oxidized in atherosclerosis?

An oxidized LDL is inflammatory. And as I said, atherosclerosis is indirectly caused by inflammation. To prevent LDL to become oxidized, we have to avoid free radicals, which means we have to stay away from toxins (tobacco, air pollution, several chemicals, contaminated food/water) and oxidized food. read more

The oxidation hypothesis of atherosclerosis, summarized in 1989 by Steinberg, Whitman, and colleagues, suggests that oxidative modification of LDL plays a crucial role and that oxidized LDL (OxLDL) promotes the immune and inflammatory reactions that characterize atherosclerosis . At the most basic level, oxidation is the loss of electrons. read more

Oxidized low density lipoprotein (ox-LDL), a risk factor of atherosclerosis, facilitates the formation and vulnerability of atherosclerotic plaque, thus contributing to several clinical complications. Stem cells participate in vascular repair after damage and atherosclerosis is a process of inflammation accompanied with vascular injury. read more