In the examples given in Preet Dhunna and Tom Bejma's answers, they point out that a rear wheel drive tadpole may have a larger rear wheel as that is the driven wheel and the larger size produces more torque for the same amount of drive line input. read more
So if the front wheel is bigger then the rear wheel it will create a pressure difference between the rear and front end of the fuel line. So fuel from your fuel tank will not be able to flow to engine efficiently, plus it will lead fuel wastage. read more
When the car does slip out of control on a fast turn, we can design it in such a way that we know whether the front or rear wheels will slip first. This is important because if the rear wheels slip first, the vehicle runs the risk of spinning out of control (oversteer). read more