They are both part of the endomembrane system. When a cell makes proteins, it starts by transcribing RNA from the DNA located inside its nucleus. RNA is then carried out of the nucleus into the rough endoplasmic reticulum. There, the RNA meets up with a ribosome, which are attached to the ER.May 2, 2015 read more
Endoplasmic reticulum (ER), in biology, a continuous membrane system that forms a series of flattened sacs within the cytoplasm of eukaryotic cells and serves multiple functions, being important particularly in the synthesis, folding, modification, and transport of proteins. read more
The rough endoplasmic reticulum works in concert with the Golgi complex to target new proteins to their proper destinations. A second method of transport out of the endoplasmic reticulum involves areas called membrane contact sites, where the membranes of the endoplasmic reticulum and other organelles are held closely together, allowing the transfer of lipids and other small molecules. read more