Top Ten Strangest Diseases
Congenital insensitivity to pain is a condition, present from birth, that inhibits the ability to perceive physical pain. Affected individuals are unable to feel pain in any part of their body. Over time, this lack of pain awareness can lead to an accumulation of injuries and health issues that may affect life expectancy.
Moebius syndrome is a rare neurological condition that primarily affects the muscles that control facial expression and eye movement. The signs and symptoms of this condition are present from birth. Weakness or paralysis of the facial muscles is one of the most common features of Moebius syndrome.
Hermaphroditism is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that Hermaphroditism, or a subtype of Hermaphroditism, affects less than 200,000 people in the US population.
Fibrodysplasia ossificans progressiva (FOP) is an extremely rare connective tissue disease. The disease is caused by a mutation of the body's repair mechanism, which causes fibrous tissue (including muscle, tendon, and ligament) to be ossified spontaneously or when damaged.
Central hypoventilation syndrome (CHS) is a respiratory disorder that results in respiratory arrest during sleep. CHS can either be congenital (CCHS) or acquired (ACHS) later in life. It is fatal if untreated. It is also known as Ondine's curse. ACHS can develop as a result of severe injury or trauma to the brain or brainstem.
Proteus syndrome is a rare condition characterized by overgrowth of the bones, skin, and other tissues. Organs and tissues affected by the disease grow out of proportion to the rest of the body. The overgrowth is usually asymmetric, which means it affects the right and left sides of the body differently.
Hutchinson-Gilford progeria syndrome. ... National Organization for Rare Disorders. https://rarediseases.org/rare-diseases/hutchinson-gilford-progeria/.
Most often, the small piece of skin contains no bones but does contain nerves and blood vessels. In some rarer cases, there are up to five vertebrae in the small tail, resulting in a true human tail or vestigial tail. According to experts, this human tail is not really a tail at all.