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Types of Chondrosarcoma

Clear Cell Chondrosarcoma
Clear Cell Chondrosarcoma

Clear cell chondrosarcomas represent a chondrosarcoma subtype representing 1-2% of all chondrosarcomas. They are typically low-grade (see chondrosarcoma grading) and get their name from the presence of clear cell chondrocytes which have abundant vacuolated cytoplasm due to the presence of glycogen.

Dedifferentiated Chondrosarcoma
Dedifferentiated Chondrosarcoma

Dedifferentiated chondrosarcoma was first proposed in 1971 by Dahlin and Beabout. It is characterized by two distinct histopathological components; a well-differentiated benign chondral lesion or chondrosarcoma (any grade) sharply juxtaposed with a high-grade non-cartilaginous component; typically there is an abrupt transition between the two tissue types.

Juxtacortical Chondrosarcoma
Juxtacortical Chondrosarcoma

Juxtacortical Chondrosarcoma. Definition: A malignant, subperiosteal cartilaginous tumor that lacks osteoid production and erodes the underlying cortical bone ...

Mesenchymal Chondrosarcoma
Mesenchymal Chondrosarcoma

mesenchymal chondrosarcoma A rare high-grade chondrosarcoma consisting of undifferentiated mesenchymal cells admixed with cartilage. Sites Femur, ribs, jaw, skull, and spine are most common, though it may occur in any bone. Clinical findings Pain, swelling.

Secondary Chondrosarcoma
Secondary Chondrosarcoma

Secondary chondrosarcoma is a distinctive type of tumor that originates from a preexisting cartilaginous lesion. Most commonly, it is associated with solitary or multiple osteochondromas. A fraction of cases arises from other conditions, such as Maffucci syndrome and Oilier disease.