Like other opioid medicines, hydrocodone can slow your breathing. Death may occur if breathing becomes too weak. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
What other drugs will affect hydrocodone and ibuprofen (Ibudone, Reprexain, Vicoprofen)? Before using hydrocodone and ibuprofen, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by hydrocodone and ibuprofen.