Both acetoacetate and beta-hydroxybutyrate are responsible for transporting energy from the liver to other tissues in the body. KETONE FORMATION. During the process of ketogenesis, which is when ketone bodies are formed from the breakdown of fatty acids, acetoacetate is the first ketone that’s created.
Ketone (ketone bodies) are simple, organic molecules your body produces when carb intake is restricted. The human body produces three ketone bodies as a byproduct of lipolysis: acetone, acetoacetic acid, and beta-hydroxybutyric acid (BHB). How to test ketone levels at home. Beta-hydroxybutyric acid is available as an exogenous ketone supplement.
In humans, D-β-hydroxybutyrate can be synthesized in the liver via the metabolism of fatty acids (e.g., butyrate), β-hydroxy β-methylbutyrate, and ketogenic amino acids through a series of reactions that metabolize these compounds into acetoacetate, which is the first ketone body that is produced in the fasting state.