Excess belly fat may affect breathing by pushing on the diaphragm and chest wall, making it harder for the lungs to fill with air. The American Heart Association considers a waist circumference of more than 35 inches for women or 40 inches for men to be abnormal.
Endometrial cancer: Obese and overweight women are two to about four times as likely as normal-weight women to develop endometrial cancer (cancer of the lining of the uterus), and extremely obese women are about seven times as likely to develop the more common of the two main types of this cancer .
Until recently the relation between obesity and coronary heart disease was viewed as indirect, ie, through covariates related to both obesity and coronary heart disease risk, 12 including hypertension; dyslipidemia, particularly reductions in HDL cholesterol; and impaired glucose tolerance or non–insulin-dependent diabetes mellitus.
Obesity-Depression Links. Research has shown that there's no clear, one-way connection between obesity and depression. Instead, studies have shown that the two tend to feed off each other in a vicious, self-destructive circle. Obesity causes depression.
Due to the excess weight, associated diseases may developed, including diabetes, hypertension, metabolic disease, cancer, heart disease and pulmonary disease. Both obesity and rapid weight loss are currently the main causes for the development of gallbladder disease as well: there is a connection between gallbladder disease and obesity.