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Types of Transfusion Reactions

Acute Hemolytic Reactions
Acute Hemolytic Reactions

A transfusion reaction is when your body has an adverse response to a blood transfusion. A blood transfusion is a lifesaving procedure that adds donated blood to your own. If the added blood isn’t matched to your type, you can experience a reaction. Learn how transfusion reactions occur and how to minimize your risk.

Allergic Reactions
Allergic Reactions

Allergic reactions can occur during or up to 3 hours post-transfusion. The shorter the time interval is between the start of the transfusion and the onset of the allergic reaction, the more severe the reaction. In more severe reactions, anxiety, dyspnea, palpitations, fever and chills may accompany urticaria.

Bacterial Contamination and Endotoxemia
Bacterial Contamination and Endotoxemia

Bacterial contamination/endotoxemia: The incidence of septic reactions may be as high as one case per 700 pooled random donor platelet concentrates and one case per 4000 single-donor (apheresis) platelet products.

Circulatory (Volume) Overload
Circulatory (Volume) Overload

In transfusion medicine, transfusion associated circulatory overload (TACO) is a transfusion reaction (an adverse effect of blood transfusion) that occurs due to a rapid transfusion of a large volume of blood.

Nonhemolytic Febrile Reactions
Nonhemolytic Febrile Reactions

Stop transfusion immediately and follow other steps for managing suspected transfusion reactions. Treat the fever with an antipyretic. However, avoid aspirin in thrombocytopenic and paediatric patients. Consider and exclude other causes, as fever alone may be the first manifestation of a life threatening reaction.

Transfusion-Related Acute Lung Injury (TRALI)
Transfusion-Related Acute Lung Injury (TRALI)

Transfusion-related acute lung injury (TRALI) is a rare but serious syndrome characterized by sudden acute respiratory distress following transfusion. It is defined as new, acute lung injury (ALI) during or within six hours after blood product administration in the absence of temporally-associated risk factors for ALI.