Hydrocodone is an opioid and one of two active components of Norco (with APAP). Opioid receptors exist in the GI tract and opioid agonists reduce the tone of intestinal muscle, resulting in a reduction in peristalsis (i.e. muscle movement in the gut that moves food stuff and waste along). read more
For people taking hydrocodone/APAP, constipation is a likely -- and expected -- side effect. Your healthcare provider may recommend that you take a laxative or stool softener while taking the drug to prevent this problem from occurring. read more
In less severe cases, some of the home remedies we suggest in our Guide to Constipation may be helpful. Sugarless gum can often ease difficulties, as can “Power Pudding,” which teams the power of prunes in the form of prune juice with that of wheat bran and applesauce. read more