Can you make your dopamine receptors more sensitive?

I too believe that anything which makes us too happy, when abused for long enough, will make us numb. In order to maintain homeostasis(equilibrium), when an excess amount of dopamine is released, the dopamine receptors down-regulate, thus requiring more dopamine to achieve the same level of happiness. read more

Dopamine receptors can, indeed, become super-sensitive. In fact, this is thought to be the reason people develop tardive dyskinesia after long term antipsychotic treatment. Antipsychotics all work, to one degree or another, by blocking the D2 dopamine receptor. read more

By giving your brain time to readjust itself to lower stimulation levels, you can effectively "reboot" your brain and make it more sensitive to dopamine. This manifests in increased motivation, drive, hope, and energy. read more

One signal which is paradoxical in the sense that it increases dopamine, but also makes you more sensitive to it is exercise, especially high intensity activities which involve hand eye coordination. MMA, gymnastics, dancing are all good, since they raise your heart rate and you need to engage your brain. read more