In one experiment, Roffman and colleagues scanned the brains of 100 healthy volunteers using fMRI while the volunteers were resting as well as while they were completing a working memory task. read more
Dopamine in the prefrontal cortex is known to play an important role in working memory by increasing the activity of brain circuits relevant to a task and suppressing circuits that distract from that task. read more
Keywords: dopamine, D5 dopamine receptor, working memory, prefrontal cortex, Akt, cognition, recency memory, mice Citation: Carr GV, Maltese F, Sibley DR, Weinberger DR and Papaleo F (2017) The Dopamine D5 Receptor Is Involved in Working Memory. read more