Definition. By Mayo Clinic Staff. Limited scleroderma, or CREST syndrome, is one subtype of scleroderma — a condition that literally means "hardened skin." The skin changes associated with limited scleroderma typically occur only in the lower arms and legs and sometimes the face and throat. read more
Limited scleroderma, or CREST syndrome, is one subtype of scleroderma — a condition that literally means "hardened skin." The skin changes associated with limited scleroderma typically occur only in the lower arms and legs and sometimes the face and throat. read more
Interestingly, the skin disease actually improves spontaneously after many years. The disease has so much variability from person to person that I think it is not useful to talk about life expectancy. Clearly, we still need better therapies, but many patients with milder forms of the disease have excellent outcomes. read more
Basic doctoring. We have a joke in clinical medicine -- if a $10000 workup comes back without a clear answer, do a history and physical exam. read more